WebSide Effects Management; Pharmacy; Clinical Trials. Breast Cancer Clinical Trials; Lung Cancer Clinical Trials; View All Clinical Trials; Blood Disorders. ... A Phase 1-2 Study Of Combination Therapy With INCMGA00012 (Anti PD-1), INCAGN02385 (Anti LAG-3), And INCAGN02390 (Anti TIM-3) In Participants With Select Advanced Malignancies. Learn more. WebSeven (26%) had a TEAE of special interest (the only immune-related AE occurring in >1 pt was hypothyroidism [n=2]). Two pts (7%) discontinued treatment due to TEAEs (radiculopathy and polyarthritis). No fatal TEAEs have been reported. Conclusions
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WebINCMGA00012 is an immunotherapy drug that boosts the body’s natural defenses to fight cancer. Palbociclib is already used to treat certain types of breast cancer; its use in this … WebJun 17, 2024 · Known prior severe hypersensitivity to investigational product or any component in its formulations, including known severe hypersensitivity reactions to monoclonal antibodies (NCI CTCAE v 5 Grade ≥ 3) Patients who require concomitant use of medications that strongly induce or inhibit CYP3A (per section 15.0) Study Plan slw sonic srb2
An Umbrella Study of INCMGA00012 Alone and in Combination …
WebCardiovascular: patients that have any of the following within 6 months of randomization: severe/unstable angina, myocardial infarction, symptomatic pericarditis, symptomatic congestive heart failure (New York Heart Association functional classification III-IV), cerebrovascular accident including transient ischemic attack, or symptomatic … WebINCMGA00012 is being investigated as monotherapy and in combination with other treatment modalities in clinical trials – 5 of which are also presented at SITC 2024 (P336, P313, P304, P305, P306) First-in-Human Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors: Interim Results of the Cohort Expansion Phase solar powered el wire